HORDB

ID: hor001158
Uniprot ID: D9I8P2
Protein name: PepGE
Gene name: AFP-13
Organism: Ascaris suum (Pig roundworm) (Ascaris lumbricoides)
Family: FARP (FMRFamide related peptide) family
Source: animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Ascaris (genus), Ascarididae (family), Ascaridoidea (superfamily), Ascaridomorpha (infraorder), Spirurina (suborder), Rhabditida (order), Chromadorea (class), Nematoda (phylum), Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: NA
GO BP: GO:0007218 neuropeptide signaling pathway
GO CC: GO:0005576 extracellular region

Sequence: GNSYRSFFNPNEYTVVE
Length: 17
Propeptide: MAINSISCLITMLAITVAVSTLESSEIRMLESEFLDGKRGNSYRSFFNPNEYTVVERRDSKLMDPLIRFGKRTNIMGENRLNRNLRAEGLSSPLIRFGKRTPPEEDLLGRFTRDPQQRIVTDETVLRFGRSSAPAAA
Signal peptide: MAINSISCLITMLAITVAVSTLES
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor001158_AF2.pdb

hor001158_ESM.pdb

Mass:	230868	Formula:	C91H127N23O30
Absent amino acids:	ACDHIKLMQW	Common amino acids:	N
pI:	4.26	Basic residues:	1
Polar residues:	9	Hydrophobic residues:	4
Hydrophobicity:	-87.65	Boman Index:	-4313
Half-Life:	30 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	34.12
Instability Index:	1310	Extinction Coefficient cystines:	2980
Absorbance 280nm:	186.25

PubMed ID: 20806053
Title: Mapping Neuropeptide Expression by Mass Spectrometry in Single Dissected Identified Neurons From the Dorsal Ganglion of the Nematode Ascaris Suum